Aktivitas Antijamur Fraksi Ekstrak Etanol Daun Pare (Momordica charantia L.) terhadap Microsporum canis ATCC 32699

Reza Agung Sriwijaya, Rini Isromarina, Meyla Rosada

Abstract


Pare is one of the plants used as an herbal medicine, one of which is for infectious diseases. This study aimed to evaluate the antifungal activity ethanol extract fraction leaves of Pare. The extraction was carried out using maceration method and then fractionated using n-hexane, ethyl acetate and water solvents. The antifungal activity was determined using the agar diffusion method. The test fungus was using Microsporum canis at a serial concentration of 1,5%, 1% and 0,5%. The results of antifungal activity test of n-hexane fraction, ethyl acetate fraction and water fraction of Pare leaf ethanol extract showed the existence of inhibitory zone diameter. In the n-hexane fraction, ethyl acetate and water frac-tion the diameter of the largest inhibitory zone was 11,7 mm, 11,6 mm and 10,1 mm. Inhibitory zone showed that the fraction of ethanol extract of Pare leaves has antifungal activity.

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References


Cappuccino dan James, G. 2009. Manual Laboratorium Mikrobiologi. Jakarta : Medical Publisher.

Castro.C.M.S., Vilanova, N.S., Cavalcante., Rocha, M.F.G. 2015. Antifungal Activity of Plant Extract Againts Microsporum canis and Candida spp. Strain. Boletin Latinoam Caribe Plant Med Aromat. 14(4) : 263 – 272.

Djamal, R. 2010. Kimia Bahan Alam : Prinsip-prinsip Dasar Isolasi dan Identifikasi. Padang : Universitas Bai-turrahman.

Fissy, O.N, Sari, R., Pratiwi, L. 2014. Efektivitas Gel Anti Jerawat Ekstrak Etanol Rimpang Jahe Merah (Zingiber officinale Rose) terhadap Propionibacterium acnes dan Staphylococcus epidermidis. Jurnal Ilmu Ke-farmasian Indonesia : 193-201.

Hidayat, S dan Napitupulu, M.R. 2015. Kitab Tumbu-han Obat. Jakarta : Agriflo Penebar Swadaya Timur Group.

Mada, B.S., Garba, A., Mohammed, A.H., Muhammad, A., Olagunjo, A and Muhammad, B.A. 2013. Antimi-crobial Activity and Phytochemical Screening of Aquous and Ethanol Extracts of Momordica charantia L. Journal Medicinal Plants Research. 7(10) : 579 – 586.

Maharani, A. 2015. Penyakit Kulit : Perawatan, Pence-gahan, dan Pengobatan. Yogyakarta : Pustaka Baru Press.

Muhammad, M., Ted, B.A., Rosen, M.D. 2013. Skin Theraphy Letter, No More Antibiotics for Acne. The US National Library of Medicine and Pudmed. 18(5).

Schormoulo, G., Mendonca, R.R., Alviano, C.S, Costa, S.S. Screening of Antifungal Agents Using Ethanol Pre-cipitation and Bioautography of Medical and Food Plants. Journal Ethnopharmacol. 96 : 563-568.

Soares, B.V., Morais, S.M, Fontenelle, R., Brito, E.H.S., Queiroz, V.A., Mutiara, E.D dan Wildan, A. 2014. Ek-straksi Flavonoid Daun Pare (Momordica charantia L) Berbantu Gelombang Mikro Sebagai Penurun Kadar Glukosa Secara Invitro. Metana. 10(01) : 1-11.

Tjay, TH dan Rahardja, K. 2008. Obat-obat Penting, Khasiat, Penggunaan dan Efek Sampingnya. Edisi ke-enam. Jakarta : Elex Media Komputindo.




DOI: https://doi.org/10.36706/jps.v20i2.506

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